Liposomal histidine is designed for delivery of histidine across the cell membranes.   Histidine at an internal concentration of 100 mM is encapsulated in the liposome. The external histidine concentration is 1 mM.  To ensure the delivery efficiency, the lipid composition of the liposomal histidine is the same as that for a liposomal drug in clinic which is HSPC: DSPE-PEG2000: cholesterol (3:1:1, mass ratio). The average size of liposomes is about 110 nm.

The PEGylated Liposomal Histidine (Catalog No. PHPC002HS) includes 2 ml of 100 mM histidine encapsulated in 7 mg/ml PEGylated liposomes. The external solution is 0.1 M NaCl.